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Bio-inspired materials for biomedical engineering

Anthony B Brennan Anthony B. Brennan editor of compilation.; Chelsea M. Kirschner editor of compilation.; Marta Alves da Silva contributor.

Hoboken, New Jersey : Wiley 2014

Online access

  • Title:
    Bio-inspired materials for biomedical engineering
  • Author: Anthony B Brennan
  • Anthony B. Brennan editor of compilation.; Chelsea M. Kirschner editor of compilation.; Marta Alves da Silva contributor.
  • Subjects: Biomedical materials; Biomedical engineering; Electronic books
  • Contents: Cover; Series page; Title page; Copyright page; Contents; Contributors; Preface; Introduction; PART I: Engineering Bio-inspired Material Microenvironments; CHAPTER 1: ECM-Inspired Chemical Cues: Biomimetic Molecules and Techniques of Immobilization; 1.1 Introduction; 1.2 Development and Immobilization of Biomimetic Cues in 3-D Biomaterials; 1.2.1 Synthetic Peptides Derived from Fibronectin, Laminin, and Collagen; 1.2.2 Carbohydrate-Binding Peptides; 1.2.3 Glycomimetic Peptides; 1.2.4 Growth Factors; 1.3 Spatial Orientation and Dynamic Display; 1.3.1 Spatially Controlled Display
    1.3.2 Stimuli-Sensitive Dynamic Display1.4 Future Perspectives; References; CHAPTER 2: Dynamic Materials Mimic Developmental and Disease Changes in Tissues; 2.1 Introduction; 2.2 Cell Scaffolds, Their Intrinsic Properties, and Their Effects on Cells; 2.2.1 Natural Polymers and Their Properties; 2.2.2 Synthetic Polymers and Their Properties; 2.2.3 The Effects of Scaffolds on Cells; 2.3 ECM is a Dynamic Tissue; 2.4 Dynamic Scaffolds; 2.4.1 Dynamically Stiffening Scaffolds; 2.4.2 Degradable Scaffolds; 2.5 Conclusion; Acknowledgments; References
    CHAPTER 3: The Role of Mechanical Cues in Regulating Cellular Activities and Guiding Tissue Development3.1 Introduction; 3.2 Mechanotransduction; 3.2.1 Mechanotransduction from Extracellular Matrix to Cytoplasmic Structures; 3.2.2 Mechanotransduction by Cell-ECM Adhesions; 3.2.3 Mechanotransduction by Cell-Cell Adhesions; 3.2.4 Intracellular Molecules; 3.2.5 AdhesionMediated Signaling Pathways; 3.3 Mechanotransduction from Cytoplasm to Nucleus; 3.4 Role of Mechanical Cues in Developmental Biology; 3.5 Applications of Mechanical Stimulation in Regenerative Medicine; 3.5.1 Articular Cartilage
    3.5.2 Tendon/Ligament3.5.3 Bone; 3.5.4 Blood Vessels; 3.6 Summary; References; CHAPTER 4: Contribution of Physical Forces on the Design of Biomimetic Tissue Substitutes; 4.1 Introduction; 4.1.1 Molecular Mechanisms of Cell Adhesion; 4.1.2 Cell Adhesion to Substrates; 4.2 Physical Forces; 4.2.1 Mechanical Forces; 4.2.2 Thermal Forces (NIPAM); 4.2.3 Electromagnetic Forces (Continuous, Pulsatile); 4.2.4 Hydrodynamic Forces (Shear; Pulsatile, Compression; Continuous); 4.3 Conclusion; Acknowledgments; References; CHAPTER 5: Cellular Responses to Bio-Inspired Engineered Topography
    5.1 Introduction5.1.1 Historical Introduction to Cellular Responses to Physical Cues; 5.1.2 Physical Cues in Nature; 5.2 Definition of Engineered Topography; 5.3 Surface Fabrication Techniques; 5.3.1 Fabrication of Engineered Topography; 5.4 Cellular Responses to 2-D Engineered Topographies; 5.5 Cellular Responses to Dynamic, Engineered 2-D Topographies; 5.6 Conclusions and Future Directions; Acknowledgments; References; CHAPTER 6: Engineering the Mechanical and Growth Factor Signaling Roles of Fibronectin Fibrils; 6.1 Introduction; 6.2 Structure of Fibronectin
    6.3 Assembly of Fibronectin Fibrils
    Bio-inspired concepts for biomedical engineering are at the forefront of tissue engineering and regenerative medicine. Providing a comprehensive overview of the latest advances and techniques in the field, Bio-inspired Materials for Biomedical Engineering demonstrates the dramatic clinical breakthroughs that have been made in engineering all four of the major tissue types and modulating the immune system. Written by prominent leaders in the fields of materials engineering, chemical engineering, cell biology, and regenerative medicine, this groundbreaking text provides scientists, profes
    Description based upon print version of record.
  • Publisher: Hoboken, New Jersey : Wiley
  • Creation Date: 2014
  • Physical Description: 1 online resource (416 p.).
  • Language: English
  • Identifier: ISBN1-118-84349-5;ISBN1-118-84343-6;ISBN1-118-84362-2
  • Source: 01GALI USG ALMA
  • OCLC Number: 867001316
  • NZ MMS ID: 9913747248302931

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